Edited by SOM international group chair, Dr Will Ponsonby, this new issue highlights that globally, an estimated 2.3 million workers die every year from occupational accidents and work- related diseases; this equates to 6,300 deaths daily. In addition, over 300 million workers have non-fatal occupational accidents resulting in disability and time off work. 2.3 million work-related deaths per year outnumber deaths due to tuberculosis (TB), AIDS and road accidents. The burden is particularly heavy in low and middle income countries, where manufacturing is mostly concentrated, and health and safety law and its application is often not so well implemented. This issue was launched in tandem with the “Occupational health in a global setting” SOM/RSM meeting in London on 10 May. Click here to view to the virtual issue.